Thermo Fisher Scientific ARMET Recombinant Rabbit Monoclonal Antibody (012)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal production clones.

Advantages of recombinant rabbit monoclonal antibodies:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Mouse MANF.

Target Information

The protein encoded by this gene is localized in the endoplasmic reticulum and Golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation.

Originally thought to contain an arginine-rich region at the N-terminus, later evidence indicates a smaller open reading frame without this tract. Polymorphisms in the arginine-rich region, including a mutation changing codon 50 from ATG to AGG, have been reported in various tumors, but these variants are also found in normal tissues and are not tumor-related.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.