Thermo Fisher Scientific Lactoferrin Recombinant Rabbit Monoclonal Antibody (002)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select optimal clones for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Improved specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Mouse Lactotransferrin/LTF.

Target Information

Lactoferrin (LF) is an iron-binding glycoprotein composed of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺).

LF is found in milk, mucosal secretions, and neutrophil granules. It plays key roles in:

• Iron homeostasis regulation
• Host defense against microbial infections
• Anti-inflammatory activity
• Cellular growth and differentiation regulation
• Protection against cancer development and metastasis

LTF acts as a major first-line defense against microbial infections by binding and removing Fe³⁺ and also exhibits bactericidal and proteolytic activity.
Three isoforms (LTF-α, LTF-β, LTF-γ) are known, and receptors for LTF are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and some bacteria.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.