Thermo Fisher Scientific TWISTNB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TWISTNB. Recombinant protein control fragment (Product #RP-92637). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TWISTNB,uniProtId:Q3B726-1,ncbiNodeId:9606,antigenRange:250-329,antigenLength:338,antigenImageFileName:PA5-53913_TWISTNB_Q3B726-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53913_TWISTNB_Q3B726-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2649129

Product Specific Information

Immunogen sequence: DADDTPMEES ALQNTNNANG IWEEEPKKKK KKKKHQEVQD QDPVFQGSDS SGYQSDHKKK KKKRKHSEEA EFTPPLKCSP

Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 59%.

Target Information

DNA-directed RNA polymerase I subunit RPA43 or Twist neighbor protein (Twistnb)belongs to the eukaryotic RPA43 RNA polymerase subunit family. It catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.Twistnb is the component of RNA polymerase I which synthesizes ribosomal RNA precursors. It is widely expressed in all fetal and adult tissues, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. Twist genes are essential for embryonic development and are conserved from jellyfish to human.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.