Thermo Fisher Scientific Fatty Acid Binding Protein 4 (FABP4) Monoclonal Antibody (FABP4/4424)
인간 FABP4 단백질을 인식하는 단클론 항체로, IHC(P) 등 다양한 응용에 사용 가능. 단백질 A/G 정제, PBS+BSA 완충액, 4°C 보관. 지방산 결합 단백질 연구 및 대사 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
| Immunoelectrophoresis (IE) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FABP4/4424 |
| Immunogen | Recombinant fragment (around aa1–132) of human FABP4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody is stable for 24 months.
- Positive Control: Human adipose tissue
- Cellular Localization: Cytoplasm, Nucleus
Specificity Comments:
Fatty acid-binding proteins (FABPs) are a family of cytoplasmic proteins expressed in a tissue-specific manner, playing key roles in lipid and carbohydrate metabolism. FABPs mediate fatty acid and hydrophobic ligand uptake, transport, and targeting within tissues. They are expressed in various tissues, including adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP), muscle and heart (H-FABP), intestine (I-FABP), liver (L-FABP), myelin (M-FABP), and testis (T-FABP).
The human A-FABP gene maps to chromosome 8q21.13 and encodes a 132 amino acid protein, comprising about 1% of total cytosolic protein in human adipose tissue.
Target Information
FABP4 belongs to the fatty acid binding protein (FABP) family, which facilitates transport of fatty acids and lipids in cellular pathways. It is expressed in adipocytes, macrophages, monocyte-derived dendritic cells, and myoepithelial cells, delivering long-chain fatty acids and retinoic acid to nuclear receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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