Thermo Fisher Scientific TIMD4 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal TIMD4 항체. Western blot에 적합하며, Jurkat lysate를 양성 대조로 권장. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도. 냉장 보관(2–8°C) 권장, 장기 보관 시 -20°C.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
- Suggested Positive Control: Jurkat cell lysate
- Blocking Peptide: PEP-0365
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide from near the carboxy terminus of human TIM-4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152144 |
Product Specific Information
A suggested positive control is Jurkat cell lysate.
PA5-20247 can be used with blocking peptide PEP-0365.
Target Information
The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors involved in the regulation of T helper (Th)1 and Th2 cell-mediated immunity. TIM-4, preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and, due to its connection to TIM-1-triggered Th2 responsiveness, may be considered a candidate disease/predisposition gene for asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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