Thermo Fisher Scientific CX3CL1 Polyclonal Antibody
CX3CL1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ELISA, IP 등 다양한 분석에 적합합니다. 인간, 마우스, 설치류 등 반응성이 있으며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- CX3CL1-101AP
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 350–395 on mouse Fractalkine (CX3CL1) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Chemokines are a family of proteins associated with leukocyte trafficking in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues.
CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes through membrane-bound and soluble forms, respectively.
Recent studies indicate that CX3CL1 can suppress production of nitric oxide, interleukin-6, and TNF-α in activated microglia and neuronal cells, suggesting its role as an intrinsic inhibitor of neurotoxicity.
Its receptor, CX3CR1, also acts as a co-receptor for HIV-1 and HIV-2 envelope fusion and infection, which can be inhibited by CX3CL1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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