Thermo Fisher Scientific CX3CL1 Polyclonal Antibody, Biotin
CX3CL1(Fractalkine) 단백질을 인식하는 Biotin 결합 폴리클로날 항체. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트, 비인간 영장류 반응성. Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 350–395 of mouse Fractalkine (CX3CL1) protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA and 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Chemokines are a family of proteins involved in leukocyte trafficking during immune surveillance and inflammation. CX3CL1 (Fractalkine) is a CX3C chemokine that mediates leukocyte adhesion and migration via its membrane-bound and soluble forms. It can suppress nitrous oxide, IL-6, and TNF-α production in activated microglia and neuronal cells, suggesting a neuroprotective role. Its receptor, CX3CR1, also acts as a co-receptor for HIV-1 and HIV-2 envelope fusion and infection, which can be inhibited by CX3CL1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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