Thermo Fisher Scientific Hepcidin Polyclonal Antibody
Human Hepcidin을 인식하는 Rabbit Polyclonal Antibody로, Western Blot과 IHC에 사용 가능. 합성 펩타이드를 면역원으로 사용하며, 동결건조 형태로 제공. 철 항상성 연구 및 Hepcidin 관련 단백질 분석에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:100–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mature region of human Hepcidin (HAMP) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Hepcidin.
Target Information
HAMP is involved in the maintenance of iron homeostasis and is necessary for regulating iron storage in macrophages and intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22, and 25 amino acids. These active peptides are rich in cysteines, forming intramolecular bonds that stabilize their beta-sheet structures, and they exhibit antimicrobial activity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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