Thermo Fisher Scientific Hepcidin Polyclonal Antibody
인간 Hepcidin 단백질을 인식하는 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 합성 펩타이드 항원을 사용하여 제작되었으며, 보존제가 없는 동결건조 형태입니다. 철 항상성 연구 및 Hepcidin 관련 생리 기능 분석에 활용됩니다.
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Thermo Fisher Scientific Hepcidin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:100–1:2,000 | - |
| Miscellaneous (PubMed) | - | View 5 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mature region of human Hepcidin (HAMP) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Hepcidin
Target Information
HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages and for intestinal iron absorption.
The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids. These peptides are rich in cysteines, forming intramolecular bonds that stabilize their beta-sheet structures and exhibit antimicrobial activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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