Thermo Fisher Scientific Phospho-GluR1 (Ser831) Polyclonal Antibody
Phospho-GluR1 (Ser831) 항체로 인간, 생쥐, 랫트 시료에 반응. Western blot 및 면역조직화학에 사용 가능. 항원 친화 크로마토그래피로 정제된 rabbit polyclonal IgG. -20°C 보관, 방부제 없음. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 4 publications |
| Immunohistochemistry - Free Floating (IHC (Free)) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide derived from the rat GluR1 protein (aa 831) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES (pH 7.5), 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533279 |
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor.
L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
Binding of L-glutamate induces a conformational change that opens the cation channel, converting chemical signals into electrical impulses.
The receptor rapidly desensitizes and enters a transient inactive state characterized by a bound agonist.
In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization, resulting in delayed accumulation of current flux upon continued glutamate application.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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