Thermo Fisher Scientific XRCC5 (Ku86/Ku80) (Thyroid-Lupus Autoantigen) Monoclonal Antibody (XRCC5/7316)
인간 XRCC5(Ku86/Ku80) 단백질을 인식하는 단클론 항체로, Western blot 및 면역조직화학(IHC)에 사용 가능. 단백질 손상 복구 연구에 적합하며, 고순도 Protein A/G 정제 및 안정적 액상 형태로 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / Ig Mix |
| Class | Monoclonal |
| Type | Antibody |
| Clone | XRCC5/7316 |
| Immunogen | Recombinant fragment (around aa300–500) of human XRCC5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku functions as the DNA-binding component of the DNA-dependent protein kinase and works with the DNA ligase IV–XRCC4 complex in repairing DNA double-strand breaks via non-homologous end joining and completing V(D)J recombination events. A rare microsatellite polymorphism in this gene is associated with cancer and varying radiosensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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