Thermo Fisher Scientific CYR61 Polyclonal Antibody, HRP
CYR61 단백질을 인식하는 HRP 결합 폴리클로날 항체로, Western blot 및 IHC(파라핀) 실험에 적합. 사람, 마우스, 토끼 반응성. 항원 친화 크로마토그래피로 정제된 고순도 액상 제형. 4°C 암소 보관, 연구용 전용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:200
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rabbit |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide made to the human CYR61 protein sequence (between residues 150–250) |
| Conjugate | HRP |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_11155398 |
Product Specific Information
This antibody is predicted to react with rat and mouse based on 88% sequence homology.
Target Information
CYR61 is a secreted heparin-binding protein encoded by a growth factor-inducible immediate-early gene. It associates with the extracellular matrix and connective tissue and belongs to the CCN family of angiogenic regulators, including CTGF and Fisp12.
CYR61 binds to integrin αvβ3, promoting cell adhesion, migration, and DNA synthesis in human vascular endothelial cells. Its expression increases during vessel growth, wound healing, and chondrocyte differentiation. CYR61 is often detected in tumors, where it induces growth and serves as a marker of tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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