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Thermo Fisher Scientific Phospho-c-Raf (Tyr340, Tyr341) Polyclonal Antibody
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Thermo Fisher Scientific Phospho-c-Raf (Tyr340, Tyr341) Polyclonal Antibody

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인간, 생쥐, 랫드 시료에 반응하는 phospho-c-Raf (Tyr340, Tyr341) 폴리클로날 항체입니다. Western blot과 IHC에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 연구용으로만 사용됩니다.

카탈로그번호
44506G
판매단위
pk
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마지막 업데이트 2025. 08. 04. 오후 03:33
Thermo Fisher Scientific 44506G Phospho-c-Raf (Tyr340, Tyr341) Polyclonal Antibody 100 ul pk판매 단위 pk ·
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639,300원VAT 포함 703,230원

Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-c-Raf (Tyr340, Tyr341) Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution Publications
Western Blot (WB) 1:1,000 View 2 publications
Immunohistochemistry (IHC) Assay-dependent -

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Published Species Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen The antibody was produced against a chemically synthesized phosphopeptide derived from a region of human c-Raf that contains tyrosines 340 and 341. The sequence is conserved in mouse and rat.
Conjugate Unconjugated
Form Liquid
Purification Antigen affinity chromatography
Storage Buffer Dulbecco’s PBS, pH 7.3, with 1 mg/mL BSA
Contains 0.05% sodium azide
Storage Conditions -20°C
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2533672

Target Information

Raf-1 (c-Raf) is a MAP kinase kinase kinase (MAP3K) functioning downstream of the Ras family of membrane-associated GTPases. Once activated, Raf-1 phosphorylates and activates MEK1 and MEK2, which subsequently activate ERK1 and ERK2. Activated ERKs regulate gene expression controlling cell division, apoptosis, differentiation, and migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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