Thermo Fisher Scientific Serum Amyloid P Monoclonal Antibody (273912)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Product Specifications

Species Reactivity

Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

273912

Immunogen

Mouse myeloma cell line NS0-derived recombinant rat Pentraxin2/SAP Gln21-Ser228 (predicted) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Serum Amyloid P,uniProtId:P23680-1,ncbiNodeId:10114,antigenRange:21-228,antigenLength:228,antigenImageFileName:MA5-23975_Serum_Amyloid_P_P23680-1_House_mouse.svg,antigenImageFileNamePDP:MA5-23975_Serum_Amyloid_P_P23680-1_House_mouse_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2609143

Product Specific Information

In Western blots, 100% cross-reactivity with recombinant human (rh) Pentraxin 2 and 25% cross-reactivity with recombinant mouse (rm) Pentraxin 2 is observed. In direct ELISAs, no cross-reactivity with rhPentraxin 2 or rmPentraxin 2 is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.