Thermo Fisher Scientific VEGF Receptor 1 Polyclonal Antibody
Rabbit polyclonal antibody against human VEGF Receptor 1 (FLT1), validated for WB and ICC/IF applications. Affinity purified, unconjugated, liquid form with 0.5 mg/mL concentration. Suitable for angiogenesis-related research. For Research Use Only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FLT1 (aa 178–315) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609308 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with proteins or peptides. The antibody is affinity purified from rabbit sera generated after immunization and tested for functionality in various research applications. It is intended for Research Use Only and is non-hazardous and non-infectious.
Target Information
FLT1 (VEGFR1) is a receptor tyrosine kinase crucial for angiogenesis. It plays roles in both pathological and physiological processes, including tumor progression, diabetic retinopathy, rheumatoid arthritis, and wound healing. FLT1 may act as a negative regulator of embryonic angiogenesis by inhibiting excessive endothelial cell proliferation. In adults, it can promote endothelial cell proliferation and survival, depending on cell type. It has high affinity for VEGFA and relatively low kinase activity, possibly functioning as a negative regulator of VEGFA signaling by limiting VEGFA availability and preventing its binding to KDR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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