Thermo Fisher Scientific JunD Polyclonal Antibody
Rabbit polyclonal antibody against human JunD for WB, ICC/IF, Flow Cytometry, and ChIP applications. Reacts with human and non-human primate; predicted cross-reactivity with dog, bovine, and pig. Supplied as liquid, 0.5 mg/mL, affinity purified, stored...
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | – |
| Flow Cytometry (Flow) | – | View 1 publication |
| ChIP assay (ChIP) | 2–4 µg × 10^6 cells | – |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Mouse, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Multiple peptides against Human JunD (aa 2–16, 132–149, 299–313) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2532791 |
Product Specific Information
This antibody is predicted to react with Dog, Bovine, and Pig.
Target Information
JunD is a transcription factor encoded by the JunD gene. Its transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N-terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family. Jun proteins form dimers with Fos, ATF, and CREB family transcription factors to create the AP-1 complex, which regulates genes involved in cellular growth, proliferation, differentiation, and apoptosis. Additionally, JunD plays an important role in metabolism through modulation of the IGF-1 signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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