Thermo Fisher Scientific PDCD1/PD1/CD279 (Programmed Cell Death 1) Recombinant Rabbit Monoclonal Antibody (PDCD1/8170R)
PDCD1/PD1/CD279 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단일클론 항체. 인간 시료에 반응하며 IHC 및 ELISA에 사용 가능. 고순도 Protein A/G 정제, 액상 형태로 제공되며 안정적인 PBS 버퍼에 보존. 연구용으로 적합.
- 카탈로그번호
- 5133-RBM17-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PDCD1/PD1/CD279 (Programmed Cell Death 1) Recombinant Rabbit Monoclonal Antibody (PDCD1/8170R)
Applications
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PDCD1/8170R |
| Immunogen | Recombinant fragment (around aa1–200) of human PDCD1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cell-mediated immune responses are initiated by T lymphocytes that are stimulated by peptides bound to MHC molecules on antigen-presenting cells (APC).
Activated T cells express receptors such as PD-1 (PDCD-1) that mediate inhibitory signals from the APC. PD-1 binds two related ligands, PDL-1 and PDL-2.
Upon ligand binding, PD-1 inhibits immune activation in the absence of danger signals such as LPS or pathogen-associated molecules.
PD1-deficient mice exhibit hyperactivated immune systems and autoimmune diseases.
Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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