Thermo Fisher Scientific ALDH3A1 Monoclonal Antibody (OTI1C6), TrueMAB
ALDH3A1 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC, Flow cytometry에 사용 가능. 인간 시료 반응성. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C6 |
| Immunogen | Full length human recombinant protein of human ALDH3A1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Aldh3A1 belongs to the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide range of aldehydes.
It is highly expressed in the stomach and cornea, where it can represent up to 50% of the water-soluble protein fraction.
Aldh3A1 protects the cornea from UV-induced oxidative stress through detoxification of reactive aldehydes and absorption of UV energy.
Although Aldh3A1-deficient mice show no corneal abnormalities, double knockout mice (Aldh3A1 and Aldh1A1) exhibit increased cataract formation after UVB exposure, suggesting compensatory roles between these enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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