Thermo Fisher Scientific Cytokeratin 5/6 Monoclonal Antibody (D5/16 B4)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

-

View 12 publications 12 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:25-1:50

View 5 publications 5 publications

Miscellaneous PubMed (Misc)

-

View 5 publications 5 publications

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

D5/16 B4

Immunogen

Cytokeratin 5 (Human).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

purified

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1955731

Product Specific Information

Recommended positive controls: Skin.

Product requires high temperature antien unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.

Target Information

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.