Thermo Fisher Scientific Cyclosporin A Monoclonal Antibody (CSZ.22)
Cyclosporin A를 검출하는 Mouse IgG1 단클론 항체로 ELISA 등 연구용 분석에 적합. 단백질 G 정제, 5 mg/mL 농도의 액상 형태. 4°C 보관, 동결 금지. 연구용으로만 사용 가능.
- 카탈로그번호
- MA191110
- 판매단위
- pk
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Thermo Fisher Scientific Cyclosporin A Monoclonal Antibody (CSZ.22)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CSZ.22 |
| Immunogen | Proprietary immunogen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1955642 |
Product Specific Information
MA1-91110 detects Cyclosporin A from various samples.
Target Information
Cyclosporine is a natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea.
The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin.
This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0- or G1-phase of the cell cycle.
T-lymphocytes are preferentially inhibited with T-helper cells as the primary target.
Cyclosporine also inhibits lymphokine production and release.
[National Center for Biotechnology Information. PubChem Compound Database; CID=5284373]
Usage Notice
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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