Thermo Fisher Scientific CD28 Monoclonal Antibody (3E12)
인간 CD28 항원을 인식하는 Mouse IgG1 단일클론 항체로, WB 및 ELISA에 적합합니다. 액상 형태이며 PBS buffer에 보존되어 있습니다. T 세포 활성화 연구용으로 사용되며, 연구 전용(RUO) 제품입니다.
- 카탈로그번호
- H00000940-M09
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD28 Monoclonal Antibody (3E12)
Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E12 |
| Immunogen | CD28 (NP_006130.1, 18 a.a. ~152 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GNKILVKQSP MLVAYDNAVN LSCKYSYNLF SREFRASLHK GLDSAVEVCV VYGNYSQQLQ VYSKTGFNCD GKLGNESVTF YLQNLYVNQT DIYFCKIEVM YPPPYLDNEK SNGTIIHVKG KHLCPSPLFP GPSKP
Target Information
CD28 antigen is a 44 kDa disulfide-linked homodimeric T cell-specific surface glycoprotein.
It is a cell adhesion molecule of the immunoglobulin superfamily, constitutively expressed on most peripheral blood T lymphocytes.
CD28 is the critical T cell costimulatory receptor that provides the second activation signal by binding CD80 and CD86 on antigen-presenting cells.
It prevents T cells from entering an anergic state or undergoing premature apoptotic death.
In murine lymphoid organs and blood, all CD4+ and CD8+ T cells express CD28.
CD28 dysfunction is associated with diseases such as mycosis fungoides and Sezary’s Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.