Thermo Fisher Scientific E-Cadherin (CDH1)/CD324 Recombinant Rabbit Monoclonal Antibody (CDH1, 2208R)
E-Cadherin(CDH1) 단백질을 표적하는 Thermo Fisher의 재조합 토끼 단클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. 인간 및 마우스 반응성, 비결합형 액상 형태, 고순도 Protein A/G 정제. 암 연구 및 세포 접착 관련 연구에 적합.
- 카탈로그번호
- 999-RBM8-P1ABX
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific E-Cadherin (CDH1)/CD324 Recombinant Rabbit Monoclonal Antibody (CDH1, 2208R)
Thermo Fisher Scientific E-Cadherin (CDH1)/CD324 Recombinant Rabbit Monoclonal Antibody (CDH1, 2208R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CDH1, 2208R |
| Immunogen | Recombinant full-length human E-Cadherin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C (preferred) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- This antibody does not react with Mouse or Rat.
- For immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
E-Cadherin (epithelial cadherin) is a classical cadherin from the calcium-dependent adhesion protein superfamily. It is a glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail.
Mutations in the CDH1 gene are associated with gastric, breast, colorectal, thyroid, and ovarian cancers. Loss of E-Cadherin function contributes to cancer progression by enhancing proliferation, invasion, and metastasis.
The protein plays a key role in maintaining tissue architecture and integrity. In humans, E-Cadherin is encoded by the CDH1 gene located on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.