Thermo Fisher Scientific Robo1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:300–1:2,000
• Publications: View 4 publications

Immunohistochemistry (IHC)

• Tested Dilution: 1:300–1:2,000
• Publications: View 4 publications

Miscellaneous PubMed (Misc)

• Publications: View 4 publications

Product Specifications

Product Specific Information

• Reconstitute in 100 µL of sterile water.
• Centrifuge to remove any insoluble material.
• Specificity: Robo1.

Target Information

Specialized cells at the midline, which separates the left and right halves of the CNS, play key roles in directing growth cone behavior. In vertebrates, insects, and C. elegans, midline cells produce guidance cues such as nectins and slit, which act as attractants and repellents. Robo proteins serve as axon guidance receptors for Slit, functioning in a cell-autonomous manner. Non-crossing axons express high levels of Robo, while crossing axons show dynamic expression changes before and after crossing the midline. Robo1 and Robo2 are human homologs of the Drosophila Roundabout protein. Robo1 is homologous to the C. elegans gene sax3, and Robo2 to the zebrafish gene astray.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

제품 이미지

(이미지 파일명: OSR00359W-100UL_ROBO1_O89026-1_Rabbit.svg, OSR00359W-100UL_ROBO1_O89026-1_Rabbit_PDP.jpeg)