Thermo Fisher Scientific PP1 alpha Polyclonal Antibody
Western blot, ICC/IF, ELISA에 적합한 PP1 alpha 폴리클로날 항체. Human, Mouse, Rat 반응성. Rabbit IgG 유래, 비결합형 액상 항체. 친화 크로마토그래피 정제, -20°C 보관. 세포질 및 핵 내 단백질 검출에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 230–330 of human PPP1CA (NP_002699.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.58 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805000 |
Product Specific Information
- Positive Samples: DU145, MCF7, NIH3T3, HepG2, Mouse brain
- Cellular Location: Cytoplasm, Nucleus, nucleolus, nucleoplasm
- Immunogen Sequence:
EVVAKFLHKH DLDLICRAHQ VVEDGYEFFA KRQLVTLFSA PNYCGEFDNA GAMMSVDETL MCSFQILKPA DKNKGKYGQF SGLNPGGRPI TPPRNSAKAK K
Target Information
This gene encodes a reticuloplasmin, a protein residing in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family but lacks the thioredoxin motif, suggesting it does not function as a disulfide isomerase. It dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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