Thermo Fisher Scientific MSRA Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

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Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-235 of human MSRA (NP_0364631) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MSRA,uniProtId:Q9UJ68-1,ncbiNodeId:9606,antigenRange:24-235,antigenLength:235,antigenImageFileName:PA5-88562_MSRA_Q9UJ68-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88562_MSRA_Q9UJ68-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.21 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804997

Product Specific Information

Immunogen sequence: GNSASNIVSP QEALPGRKEQ TPVAAKHHVN GNRTVEPFPE GTQMAVFGMG CFWGAERKFW VLKGVYSTQV GFAGGYTSNP TYKEVCSEKT GHAEVVRVVY QPEHMSFEEL LKVFWENHDP TQGMRQGNDH GTQYRSAIYP TSAKQMEAAL SSKENYQKVL SEHGFGPITT DIREGQTFYY AEDYHQQYLS KNPNGYCGLG GTGVSCPVGI KK; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Cytoplasm, Lipid-anchor, Membrane, Mitochondrion, Nucleus

Target Information

Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer`s disease in mammals.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.