Thermo Fisher Scientific AMHR2 Recombinant Rabbit Monoclonal Antibody (ARC1313)
AMHR2 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, 고순도의 Affinity Chromatography 정제 방식으로 제조되었습니다. 안정한 액상 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1313 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 50–150 of human AMHR2 (NP_065434.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849622 |
Product Specific Information
Immunogen sequence:
PRAIRCLYSR CCFGIWNLTQ DRAQVEMQGC RDSDEPGCES LHCDPSPRAH PSPGSTLFTC SCGTDFCNAN YSHLPPPGSP GTPGSQGPQA APGESIWMALV
Target Information
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by two discrete hormones produced by the fetal testis:
- Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth.
- Anti-Mullerian hormone (AMH) results in regression of Mullerian ducts, which would otherwise differentiate into the uterus and fallopian tubes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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