Thermo Fisher Scientific AMHR2 Recombinant Rabbit Monoclonal Antibody (ARC1313)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1313

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human AMHR2 (NP_0654341) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AMHR2,uniProtId:Q16671-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:573,antigenImageFileName:MA5-35722_AMHR2_Q16671-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35722_AMHR2_Q16671-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849622

Product Specific Information

Immunogen sequence: PRAIRCLYSR CCFGIWNLTQ DRAQVEMQGC RDSDEPGCES LHCDPSPRAH PSPGSTLFTC SCGTDFCNAN YSHLPPPGSP GTPGSQGPQA APGESIWMAL V

Target Information

The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.