Thermo Fisher Scientific ADAMTS17 Polyclonal Antibody

Thermo Fisher Scientific ADAMTS17 Polyclonal Antibody

Applications

• Immunocytochemistry (ICC/IF): 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
QVRRCNLHPCQ SRWVAGPWSP CSATCEKGFQ HREVTCVYQL QNGTHVATRP LYCPGPRPAA VQSCEGQDCL SIWEASEWS

Highest antigen sequence identity to the following orthologs:

• Mouse: 88%
• Rat: 89%

Target Information

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may promote breast cancer cell growth and survival. Mutations in this gene are associated with a Weill-Marchesani-like syndrome characterized by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature.
[provided by RefSeq, May 2016]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.