Thermo Fisher Scientific Ephrin Receptor B1 Polyclonal Antibody
Thermo Fisher Scientific의 Ephrin Receptor B1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 rabbit IgG 기반 항체입니다. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합하며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
- 카탈로그번호
- EPHBR1-101AP
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 850–900 on mouse EphB1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
EPHB1 is a receptor tyrosine kinase belonging to the ephrin receptor family. Members of the Eph family play key roles in biological processes such as nervous system development, angiogenesis, and neural synapse formation and maturation. EphB1 and other EphB family members are type I membrane-spanning proteins with immunoglobulin, fibronectin type III, and cysteine-rich subdomains in the ectodomain, and a single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. EphB family proteins bind ephrins of the B class, which are transmembrane ligands capable of bidirectional signaling. EphB1 is predominantly expressed in developing neural structures and vascular epithelium of kidney and other tissues. Upon binding to oligomerized ephrin B1, EphB1 regulates cell attachment and assembly. Members of this family are implicated in neuronal and vascular cell targeting.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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