Thermo Fisher Scientific RPS19 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total RPS19.

Target Information

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
This gene encodes a ribosomal protein that is a component of the 40S subunit and belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm.
Mutations in this gene cause Diamond-Blackfan anemia, a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function.
Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues have been observed.
As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.