Thermo Fisher Scientific ERK2 Internal Polyclonal Antibody, FITC

Thermo Fisher Scientific ERK2 Internal Polyclonal Antibody, FITC

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at 4°C prior to restoration.
• For extended storage, aliquot contents and freeze at -20°C or below.
• Avoid cycles of freezing and thawing.
• Centrifuge product if not completely clear after standing at room temperature.
• Stable for several weeks at 4°C as an undiluted liquid.
• Dilute only prior to immediate use.
• This fluorescein-conjugated affinity purified antibody is directed against human ERK2 protein.
• Cross-reactivity expected with human, mouse, and rat based on sequence identity of the peptide immunogen.
• Does not react with ERK1 isoform.

Target Information

MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.
MAP kinases (ERKs) integrate multiple biochemical signals and participate in cellular processes such as proliferation, differentiation, transcription regulation, and development.
Activation requires phosphorylation by upstream kinases, after which ERK2 translocates to the nucleus to phosphorylate nuclear targets.

For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.

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