Thermo Fisher Scientific PKM2 Monoclonal Antibody (OTI1E7), TrueMAB
PKM2 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1E7). IHC(P)에서 1:150 희석으로 검증됨. 합성 펩타이드 면역원 사용. 인간 시료에 반응하며, 액상 형태로 -20°C 보관. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E7 |
| Immunogen | Synthetic peptide sequence corresponding to the region encoded by PKM gene M2 isoform |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Synthetic peptide sequence: LRRLAPITSDPTEATAVGAV
Target Information
PKM2 (Pyruvate Kinase M2) catalyzes the conversion of phosphoenolpyruvate from pyruvate and ATP.
It interacts with thyroid hormone and may mediate metabolic effects induced by thyroid hormones.
PKM2 also binds the bacterial Opa protein, suggesting involvement in bacterial pathogenesis.
Three alternatively spliced transcript variants encoding two distinct isoforms of PKM2 have been reported.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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