Thermo Fisher Scientific SIAH1 Polyclonal Antibody
SIAH1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. Human, Mouse, Rat 반응성을 가지며, PBS 기반 용액 형태로 제공됩니다. Affinity chromatography로 정제되어 안정적인 결과를 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SIAH1 (Accession Q8IUQ4), corresponding to amino acid residues M1–N33 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852012 |
Product Specific Information
Antibody detects endogenous levels of total SIAH1.
Target Information
This gene encodes a protein that is a member of the seven in absentia homolog family. The protein acts as an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. Its activity is implicated in the development of certain forms of Parkinson’s disease, the regulation of the cellular response to hypoxia, and induction of apoptosis.
Alternative splicing results in several transcript variants, some encoding different isoforms and others not fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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