Thermo Fisher Scientific MRPL28 Polyclonal Antibody
MRPL28 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되어 높은 순도를 제공합니다. PBS 버퍼와 50% 글리세롤에 보존되며 연구용으로 사용됩니다.
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Thermo Fisher Scientific MRPL28 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human MRPL28 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720573 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).
Target Information
MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein belonging to the ribosomal protein L28P family. MRP-L28 may serve as an important therapeutic reagent for HLA-A24 (A24) patients, as it is recognized by tumor-infiltrating lymphocyte (TIL) 1290 targeting the A24 serotype.
HLA-A24 (A24) identifies common HLA-A24 gene products and is associated with the A9 broad antigen type and similar A23 types. A24 is prevalent among Austronesian populations, including Papua New Guineans, indigenous Taiwanese, Yupik, and Greenland Eskimos.
MRP-L28 is expressed in various normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung, and retinal tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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