Thermo Fisher Scientific CIDEC Polyclonal Antibody
Thermo Fisher Scientific CIDEC Polyclonal Antibody는 인간 CIDEC 단백질을 검출하는 토끼 IgG 기반 항체로, WB 및 IHC(P) 실험에 적합합니다. 고순도 친화성 크로마토그래피 정제, 액상 형태, -20°C 보관 조건을 제공합니다.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CIDEC (Accession Q96AQ7), corresponding to amino acid residues A100–L150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852731 |
Product Specific Information
Antibody detects endogenous levels of total CIDEC.
Target Information
DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently, a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are two transcripts, CIDE-3 and CIDE-3α, present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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