Thermo Fisher Scientific CDCA7L Polyclonal Antibody
Rabbit polyclonal antibody against human CDCA7L for WB and IHC applications. Detects endogenous CDCA7L protein. Supplied unconjugated in liquid form, purified by affinity chromatography. Suitable for research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CDCA7L (Accession Q96GN5), corresponding to amino acid residues M219–M269 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852733 |
Product Specific Information
Antibody detects endogenous levels of total CDCA7L.
Target Information
Cell division cycle-associated 7-like protein (CDCA7L, also known as RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to promoter regions. CDCA7L plays an oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-103389_CDCA7L_Q96GN5-1_Rabbit.svg)
(이미지: PA5-103389_CDCA7L_Q96GN5-1_Rabbit_PDP.jpeg)
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