Thermo Fisher Scientific CDK6 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CDK6. Validated for WB and IP applications. Supplied as liquid, 1 mg/mL concentration, stored at 4°C. Predicted cross-reactivity with mouse. For research use only.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 250–300 of human Cyclin-dependent kinase 6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse.
Target Information
CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with Cyclin D1 and acts as a critical regulator of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle, while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene result in microcephaly 12, primary, autosomal recessive (MCPH12).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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