Thermo Fisher Scientific WNT6 Polyclonal Antibody
WNT6 단백질을 인식하는 Thermo Fisher Scientific의 sheep 유래 polyclonal antibody. Western blot 및 IHC(P) 검증 완료. 인간 시료 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용으로만 사용 가능.
- 카탈로그번호
- PA547580
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human Wnt-6 Met35–Glu75 and Gln238–Arg299 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2576272 |
Product Specific Information
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant mouse Wnt-4, Wnt-8a, and Wnt-9b is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The WNT gene family encodes secreted signaling proteins involved in oncogenesis and developmental processes such as cell fate regulation and embryonic patterning.
WNT6 is overexpressed in cervical and colorectal cancer cell lines, often coexpressed with WNT10A.
It may play key roles in carcinogenesis. WNT6 and WNT10A are clustered in chromosome 2q35.
The human WNT6 protein shares 97% amino acid identity with the mouse Wnt6 protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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