Thermo Fisher Scientific GTF2E1 Polyclonal Antibody
GTF2E1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, ICC/IF, ELISA 등 다양한 응용에 적합. 고순도 Affinity Chromatography 정제, 액상 형태로 제공. 인체, 마우스, 랫트 반응성.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 230–439 of human GTF2E1 (NP_0055042) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.82 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806033 |
Product Specific Information
Immunogen sequence:
LAGGHHREAW ATKGPSYEDL YTQNVVINMD DQEDLHRASL EGKSAKERPI WLRESTVQGA YGSEDMKEGG IDMDAFQERE EGHAGPDDNE EVMRALLIHE KKTSSAMAGS VGAAAPVTAA NGSDSESETS ESDDDSPPRP AAVAVHKREE DEEEDDEFEE VADDPIVMVA GRPFSYSEVS QRPELVAQMT PEEKEAYIAM GQRMFEDLFE
Positive Samples: HeLa, Jurkat, A-431, Mouse brain, Mouse spleen, Mouse testis
Cellular Location: Nucleus
Target Information
The general transcription factor TFIIE plays an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors.
Human TFIIE consists of two subunits (TFIIE-alpha, 57 kDa and TFIIE-beta, 34 kDa) that join the preinitiation complex after RNA polymerase II and TFIIF.
TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in vitro.
Its sequence contains structural motifs such as leucine repeat, zinc finger, and helix-turn-helix, suggesting direct involvement in transcription regulation.
⚠ WARNING: This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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