Thermo Fisher Scientific CaMKII Pan Recombinant Rabbit Monoclonal Antibody (7L9F0)
CaMKII Pan 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, IHC, ELISA 등 다양한 연구용 응용에 적합. 높은 특이성과 재현성을 제공하며, 인간, 생쥐, 랫드 시료에 반응. -20°C에서 안정적으로 보관 가능.
- 카탈로그번호
- MA537813
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific CaMKII Pan Recombinant Rabbit Monoclonal Antibody (7L9F0)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:800 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7L9F0 |
| Immunogen | Synthetic peptide corresponding to amino acids 200–300 of human CaMKII (NP_7419601) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.3) with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | −20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2897737 |
Product Specific Information
- Positive Samples: Mouse brain, Rat brain, C6, SH-SY5Y, U-251MG
- Immunogen Sequence:
GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT VTPEAKDLIN KMLTINPSKR ITAAEALKHP WISHRSTVAS CMHRQETVDC LKKFNARRKL K
Target Information
Ca²⁺/calmodulin-dependent protein kinases (CaM kinases) are a subfamily of serine/threonine kinases including CaMKI, CaMKII, and CaMKIV.
CaMKII is a ubiquitously expressed serine/threonine protein kinase activated by Ca²⁺/calmodulin binding and autophosphorylation. It regulates cell cycle and transcription, and is involved in dendritic spine and synapse formation, neuronal plasticity, and sarcoplasmic reticulum Ca²⁺ transport in skeletal muscle.
In neurons, CaMKII plays a structural role in actin cytoskeleton reorganization during plasticity by binding and bundling actin filaments independent of its kinase activity.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: MA5-37813_CaMKII_Pan_Q13554-1_Rabbit_PDP.jpeg, MA5-37813_CaMKII_Pan_Q13554-1_Rabbit.svg)
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