Thermo Fisher Scientific CNR2 Polyclonal Antibody
CNR2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human 및 Rat 시료에 반응합니다. WB, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific CNR2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:50–1:500 | View 3 publications |
| Immunohistochemistry (IHC) | – | View 6 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:100 | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:500 | – |
| Flow Cytometry (Flow) | Assay-dependent | – |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Rat |
| Published Species | Hamster, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | GST fusion protein containing the first 32 amino acid residues from Rat CB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol, 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2082908 |
Product Specific Information
PA1-746A detects cannabinoid receptor 2 (CB2) from human and rat tissues as well as transfected rat CB2.
It has been successfully used in WB, immunocytochemistry, immunohistochemistry (paraffin), and FACS procedures.
Immunocytochemical staining of CB2 in AtT20 cells transfected with the rat CB2 gene using PA1-746 shows a pattern consistent with plasma membrane staining.
Target Information
Cannabinoids exert their physiological effects through two G protein-coupled receptors, cannabinoid receptor 1 (CB1) and CB2.
Both receptors inhibit adenylyl cyclase and stimulate MAPK activity. CB1 receptors also modulate ion channels via G-protein interactions.
Delta 9-tetrahydrocannabinol and related ligands likely exert psychoactive effects by inhibiting presynaptic calcium channels.
CB2 is primarily expressed in the immune system but may also be present in the central nervous system, including the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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