
Thermo Fisher Scientific SDHB Monoclonal Antibody (OTI1E4), TrueMAB
SDHB 단백질을 인식하는 Mouse IgG1 단클론 항체로, Human, Mouse, Rat에 반응합니다. Western blot 검증 완료. Lyophilized 형태로 제공되며 재구성 후 1 mg/mL 농도. 미토콘드리아 호흡 사슬 복합체 II 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E4 |
| Immunogen | Full length human recombinant protein of human SDHB produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Complex II of the mitochondrial respiratory chain is involved in succinate oxidation and electron transfer from FADH to CoQ.
It consists of four nuclear-encoded subunits located in the inner mitochondrial membrane.
The iron-sulfur subunit contains three cysteine-rich clusters forming iron-sulfur centers.
Mutations in this gene are associated with paragangliomas and pheochromocytoma, linking mitochondrial dysfunction to tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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