Thermo Fisher Scientific IL1B Monoclonal Antibody (OTI1A7), TrueMAB
Human IL1B 단백질을 인식하는 마우스 모노클로날 항체로 Western blot에 최적화되어 있습니다. TrueMAB 포맷으로 고순도 정제된 액상 제품이며, PBS/BSA/glycerol 버퍼에 보존됩니다. 염증성 사이토카인 연구용으로 적합합니다.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A7 |
| Immunogen | Full length human recombinant protein of human IL1B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin-1 beta (IL-1β) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. It is synthesized as a 31 kDa inactive pro-form in response to inflammatory stimuli and cleaved into an active 17 kDa form via inflammasome activation. IL-1β signals through IL-1RI and IL-1RII receptors and plays a key role in innate immune defense by inducing other proinflammatory cytokines and acute-phase responses. Elevated IL-1β levels are associated with chronic inflammatory conditions, and neutralizing antibodies against IL-1β have potential therapeutic value.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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