Thermo Fisher Scientific SNAI1 Monoclonal Antibody (OTI1H7), TrueMAB
SNAI1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. 인간 시료 반응성이 있으며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제 제품으로 안정적인 저장 및 반복 실험에 적합합니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H7 |
| Immunogen | Full length human recombinant protein of human SNAI1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Zinc finger protein SNAI1 (SNAIL) is a zinc finger transcriptional repressor that downregulates ectodermal gene expression within the mesoderm and contributes to mesoderm and neural crest formation.
SNAI1 is a key factor in tumor invasion, associated with E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT).
In human breast cancer, expression of SNAI1 and/or SNAI2 (Slug) correlates with E-cadherin repression, metastasis, recurrence, and poor prognosis.
Snail 1 protein expression in stroma may serve as a potential prognostic marker for colon tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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