Thermo Fisher Scientific CD86 (B7-2) Monoclonal Antibody (IL-A190), PE
소, 수지상세포 및 활성화된 B세포의 CD86 항원을 인식하는 단클론 항체. PE 형광표지로 유세포분석(Flow Cytometry)에 적합. 동결건조 형태로 제공되며, 4°C 암소 보관. 연구용으로만 사용 가능.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
- Flow Cytometry (Flow): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL-A190 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Lyophilized |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 5% sucrose, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745409 |
Additional Formats
Product Specific Information
Mouse anti-Bovine CD86 antibody, clone IL-A190 recognizes the bovine CD86 cell surface antigen, which is expressed by dendritic cells, activated macrophages, and activated B cells.
Reconstitute with 1 mL distilled water.
Target Information
CD86 is one of two ligands (the other being CD80) for CTLA4 and CD28. It acts as a costimulatory molecule in eliciting T-cell help during antigen presentation.
Antigen presentation without sufficient co-stimulation involving CD86/CD80 can induce tolerance. CD86 is a type I membrane protein belonging to the immunoglobulin superfamily and is expressed by antigen-presenting cells.
It binds to CD28 and cytotoxic T-lymphocyte-associated protein 4 (CTLA4) on T cells. The interaction with CD28 provides a costimulatory signal for T-cell activation, while binding to CTLA4 negatively regulates T-cell activation and diminishes the immune response.
Alternative splicing results in two transcript variants encoding different isoforms of CD86. Additional variants have been described but not fully characterized.
Diseases associated with CD86 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific CD90 (Thy-1) Monoclonal Antibody (CT4)
775,100원
Thermo Fisher Scientific
Thermo Fisher Scientific CD86 (B7-2) Monoclonal Antibody (IL-A190)
521,100원
Thermo Fisher Scientific
Thermo Fisher Scientific CD86 (B7-2) Monoclonal Antibody (IL-A190), PE
1,008,800원
Thermo Fisher Scientific
Thermo Fisher Scientific CD8 alpha Monoclonal Antibody (7C2B)
521,100원
Thermo Fisher Scientific
Thermo Fisher Scientific CD80 (B7-1) Monoclonal Antibody (IL-A159)
521,100원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|