Thermo Fisher Scientific CD80 (B7-1) Monoclonal Antibody (IL-A159)
소, 수지상세포 및 활성화된 B세포의 CD80 항원을 인식하는 단클론 항체입니다. Flow Cytometry에 적합하며 Protein A로 정제된 액상 형태입니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 1:25–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IL-A159 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745407 |
Additional Formats
Product Specific Information
This antibody recognizes the bovine CD80 cell surface antigen, expressed by dendritic cells, activated macrophages, and activated B cells. CD80 plays a key role in co-stimulation of T cells during the primary immune response.
Target Information
CD80 (B7-1) and CD86 (B7-2) are ligands of the T cell costimulatory molecule CD28 and the inhibitory receptor CTLA-4 (CD152). Both are expressed on professional antigen-presenting cells and are essential for T cell activation. CD80 is rapidly induced on activated B cells, EBV-transformed B cell lines, Burkitt’s lymphoma cells, follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes via binding to CD28 and CTLA4. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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