Thermo Fisher Scientific WAVE2 Recombinant Rabbit Monoclonal Antibody (SC66-05)
WAVE2 단백질을 인식하는 재조합 토끼 단클론 항체로 높은 특이성과 민감도를 제공. Western blot 및 IHC(파라핀) 실험에 최적화됨. HEK293 세포에서 발현된 단백질 A 정제 항체로 로트 간 일관성 우수. 연구용으로만 사용 가능.
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Thermo Fisher Scientific WAVE2 Recombinant Rabbit Monoclonal Antibody (SC66-05)
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC66-05 |
| Immunogen | Synthetic peptide within Human WASF2 aa 440–485 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809521 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to larger rabbit immune repertoire
Target Information
WASP and N-WASP are downstream effectors of Cdc42 involved in actin polymerization and cytoskeletal organization. The WASP family includes VASP and Mena, which regulate actin cytoskeleton dynamics.
WAVE proteins, including WAVE1 and WAVE2, mediate actin reorganization downstream of Rho GTPases.
- WAVE1 (SCAR): Expressed mainly in brain
- WAVE2: Highly expressed in peripheral blood leukocytes
- WAVE3: Forms multiprotein complex linking receptor kinases and actin
The WAVE complex transduces signals related to cell shape, motility, and function through actin-binding domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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