Thermo Fisher Scientific RUNX1 Polyclonal Antibody
RUNX1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot, ICC/IF, IP, CUT&RUN 실험에 사용 가능. 인간 및 생쥐 반응성, 항원 친화 크로마토그래피로 정제됨. 연구용으로 혈액세포 분화 및 조절 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.25–0.5 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
| Immunoprecipitation (IP) | - | 1 publication |
| CUT&RUN (C&R) | - | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 400 to the C-terminus of Human RUNX1 / AML1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980230 |
Product Specific Information
- For Western Blot, this antibody shows non-specific bands at 47 kDa and 75 kDa.
- Predicted to react with rat and chicken based on sequence homology.
Target Information
RUNX1 belongs to the mammalian RUNX family of DNA-binding proteins that regulate genes involved in cellular differentiation and cell cycle progression.
It is essential for hematopoietic stem cell generation in vascular regions such as the aorta, vitelline and umbilical arteries, yolk sac, and placenta.
RUNX1 is expressed in all tissues except brain and heart, with highest levels in thymus, bone marrow, and peripheral blood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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