Thermo Fisher Scientific Aromatase Polyclonal Antibody
Aromatase 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(F)에서 검증됨. Human 및 Dog 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4) + 1% BSA buffer에 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 450 to the C-terminus of Human Aromatase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10988538 |
Product Specific Information
- Heat mediated antigen retrieval recommended prior to tissue staining.
- This antibody is predicted to react with rabbit based on sequence homology.
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, performing three successive hydroxylations of the A ring of androgens.
Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.
The gene expresses two transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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