Thermo Fisher Scientific TERT Polyclonal Antibody
Hydra TERT 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 동결건조 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용.
- 카탈로그번호
- OST00408W-100UL
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Cnidarian |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 300–350 of hydra TERT conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: TERT.
Target Information
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity (encoded by the TERT gene) and an RNA component that serves as a template for telomere repeat synthesis.
Telomerase expression is typically repressed in postnatal somatic cells, leading to progressive telomere shortening and cellular senescence. Deregulation of telomerase expression may contribute to oncogenesis.
Studies in mice suggest telomerase also participates in chromosomal repair, as de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of TERT have been identified, though full-length sequences of some variants remain undetermined. Alternative splicing is thought to be one mechanism regulating telomerase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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