Thermo Fisher Scientific RET Polyclonal Antibody
RET 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody로, WB 및 IHC(F) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공됩니다. 신경능선 발달 및 종양 관련 RET 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 5–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse Ret Leu29–Arg637 (Phe174Ser) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608899 |
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. It transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia type IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene, with additional variants described but not biologically confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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